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Vol. 7 No. 2 (2026) Articles
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Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada Pasien Diabetes Mellitus di Kelurahan Angke, Jakarta Barat

Meiyanti Meiyanti
Universitas Trisakti
Yohana Yohana
Universitas Trisakti
Eveline Margo
Universitas Trisakti
Sisca Sisca
Universitas Trisakti
Published: May 10, 2026 Pages: 676-684
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Abstract

Lifestyle changes have contributed to the rising incidence of type 2 diabetes mellitus (T2DM) in major cities, including Jakarta. This condition requires thorough management, one aspect of which is long-term medication adherence. A primary factor that frequently triggers non-adherence is patients' limited understanding of antidiabetic drug side effects. This community service activity aimed to improve long-term medication adherence by strengthening patients' knowledge and understanding of antidiabetic drug side effects through education and direct consultation. The activity was carried out on March 6, 2026, in West Jakarta, using interactive counseling sessions and individual consultations. A total of 30 T2DM patients participated. Evaluation was performed through random blood glucose (RBG) measurement, pre-test and post-test assessments of knowledge on medication side effects consisting of 10 multiple-choice questions, and participatory observation. The results showed a statistically significant increase in the mean knowledge score from 62.3 to 84.7 (p<0.001). RBG testing revealed that 60% of participants had normal levels (<200 mg/dL), while the remaining 40% still exhibited hyperglycemia. During consultation sessions, chronic pain complaints were identified in several participants, potentially prompting unsupervised use of additional medications. The activity proceeded in an orderly manner with active participation from all attendees. The conclusion of this activity is that education and consultation proved effective in raising patient knowledge significantly as an initial step toward improving medication adherence; however, follow-up interventions addressing non-pharmacological management and pain management remain necessary.

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Author Biographies
Meiyanti Meiyanti Universitas Trisakti

Program Studi Profesi Dokter, Fakultas Kedokteran, Universitas Trisakti, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta, Indonesia

Yohana Yohana Universitas Trisakti

Program Studi Kedokteran, Fakultas Kedokteran, Universitas Trisakti, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta, Indonesia

Eveline Margo Universitas Trisakti

Program Studi Kedokteran, Fakultas Kedokteran, Universitas Trisakti, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta, Indonesia

Sisca Sisca Universitas Trisakti

Program Studi Kedokteran, Fakultas Kedokteran, Universitas Trisakti, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta, Indonesia

How to Cite
Meiyanti, M., Yohana, Y., Margo, E., & Sisca, S. (2026). Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada Pasien Diabetes Mellitus di Kelurahan Angke, Jakarta Barat. Jurnal Pengabdian Nasional (JPN) Indonesia, 7(2), 676-684. https://doi.org/10.63447/jpni.v7i2.1863
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References
Total: 25 References
  1. Agliardi, C., Guerini, F. R., Bolognesi, E., Zanzottera, M., & Clerici, M. (2023). Autoimmunity: A narrative review. Biology, 12(916), 1–16. https://doi.org/10.3390/biology12070916
  2. Al-Bari, M. A. A., Peake, N., & Eid, N. (2024). Tuberculosis-diabetes comorbidities: Mechanistic insights for clinical considerations and treatment challenges. World Journal of Diabetes, 15(5), 853–866. https://doi.org/10.4239/wjd.v15.i5.853
  3. Ameilia, A., & Sumiwi, S. A. (2023). Kajian interaksi obat pada peresepan pasien diabetes melitus di salah satu rumah sakit di Kota Bandung. Journal of Pharmaceutical and Sciences, 6(2), 445–450. https://doi.org/10.36490/journal-jps.com.v6i2.35
  4. Banday, M. Z., Sameer, A. S., & Nissar, S. (2020). Pathophysiology of diabetes: An overview. Avicenna Journal of Medicine, 10(4), 174–188. https://doi.org/10.4103/ajm.ajm_53_20
  5. Chauhan, V. S., Kalyani, A., Churihar, R., Jain, P. K., & Parmar, S. (2022). Pharmacovigilance study of oral antidiabetic drugs in patients with type 2 diabetes mellitus. International Journal of Health Sciences, 6(S4), 11576–11582. https://doi.org/10.53730/ijhs.v6ns4.11236
  1. Darmawan, R. A., Revina, R., & Yulianti, R. (2023). Hubungan pengetahuan dengan kepatuhan minum obat pada pasien diabetes tipe II di RSPAD Gatot Soebroto. Indonesian Journal of Pharmaceutical Education, 3(2), 2775–3670. https://doi.org/10.37311/ijpe.v3i2.20973
  2. Della, A., Subiyanto, P., & Maria, A. (2023). Faktor-faktor yang berhubungan dengan kepatuhan pengobatan pasien diabetes melitus tipe 2. Jurnal Keperawatan Klinis dan Komunitas, 7(2), 124. https://doi.org/10.22146/jkkk.83090
  3. Elsayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Cusi, K., Das, S. R., Gibbons, C. H., Giurini, J. M., Hilliard, M. E., Isaacs, D., Johnson, E. L., Kahan, S., Khunti, K., Kosiborod, M., Leon, J., Lyons, S. K., … Gabbay, R. A. (2023). Introduction and methodology: Standards of care in diabetes—2023. Diabetes Care, 46(Suppl. 1), S1–S4. https://doi.org/10.2337/dc23-Sint
  4. Elyasi, Z., Ghiasi, N., Khorshidi, A., Bakhtiyari, S., & Jalilian, M. (2024). The effect of a health education program on knowledge, medication adherence, and glycosylated hemoglobin in rural patients with type 2 diabetes. Current Diabetes Reviews, 22, 89–96. https://doi.org/10.2174/0115733998332358240923112144
  5. Fadhilah, H., Kasumawati, F., & Yuningsih, D. (2023). Analisis tingkat kepatuhan penggunaan obat antidiabetes oral pada pasien diabetes melitus tipe II. Edu Masda Journal, 7(2). http://openjournal.masda.ac.id/index.php/edumasda
  6. Fazriyati, M., Hakim, A., Anggraini, S. P., Setiawan, M. R., & Basori. (2023). Program bimbingan belajar dengan menggunakan metode one-on-one coaching di Desa Sidodadi. Menara Kearifan: Jurnal Pengabdian Masyarakat, 2(1), 20–34. https://uindatokaramapress.uindatokarama.ac.id/index.php/mk/article/view/2510
  7. Franco, J. V. A., Bongaerts, B., Metzendorf, M. I., Risso, A., Guo, Y., Peña Silva, L., Boeckmann, M., Schlesinger, S., Damen, J. A. A. G., Richter, B., Baddeley, A., Bastard, M., Carlqvist, A., Garcia-Casal, M. N., Hemmingsen, B., Mavhunga, F., Manne-Goehler, J., & Viney, K. (2024). Diabetes as a risk factor for tuberculosis disease. Cochrane Database of Systematic Reviews, 2024(8). https://doi.org/10.1002/14651858.CD016013.pub2
  8. Hadush, F., Beedemariam, G., Kahissay, M. H., Patel, S. A., & Habte, B. M. (2024). Patients' perceptions and knowledge of diabetes and medications: Implications for medication adherence and glycemic control in type 2 diabetes patients, Northern Ethiopia. Journal of Diabetes Research, 2024, Article 3652855. https://doi.org/10.1155/2024/3652855
  9. Haris, R. N. H., Masrida, W. O., Salam, M. R., & Azim, L. O. L. (2025). Analysis of the relationship between medication adherence and quality of life of Prolanis patients at first level health facilities in Kendari City. Research Journal of Pharmacy and Technology, 18(2), 551–556. https://doi.org/10.52711/0974-360X.2025.00082
  10. Hasani Furdiyanti, N., Putri Luhurningtyas, F., & Sari, R. (2017). Evaluasi dosis dan interaksi obat antidiabetika oral pada pasien diabetes mellitus tipe II. Jurnal Farmasi Sains dan Komunitas, 7(Dm), 191–196.
  11. Kaur, P., Kumar, M., Parkash, J., & Prasad, D. N. (2019). Oral hypoglycemic drugs: An overview. Journal of Drug Delivery and Therapeutics, 9(s), 770–777. http://jddtonline.info
  12. Kementerian Kesehatan RI. (2018). Laporan nasional Riskesdas 2018. Badan Penelitian dan Pengembangan Kesehatan.
  13. Kurniyawati Ningrum, D. (2020). Faktor-faktor yang berhubungan dengan kepatuhan minum obat antidiabetes pada pasien diabetes melitus tipe 2. HIGEIA Journal of Public Health Research and Development, 4(3). https://doi.org/10.15294/higeia.v4iSpecial3/36213
  14. Lestari, P., Liyanovitasari, & Prabowo, H. (2025). Medication adherence in patients with diabetes mellitus and influencing factors in Indonesia. Diabetes Mellitus, 28(2), 237–242.
  15. Molteni, L., Marelli, G., Castagna, G., Brambilla, L., Acerbis, M., Alberghina, F., Carpani, A., Chiavenna, E., Ferlini, M. G., Paredi, R., Rigamonti, A., Rivolta, G., & Disoteo, O. E. (2024). Chronic pain and diabetes: A bidirectional relationship. Endocrine, Metabolic & Immune Disorders—Drug Targets, 24, 1422–1430.
  16. Pasaribu, S., & Hutagaol, N. S. M. (2025). Strategi pembelajaran aktif untuk meningkatkan keterlibatan siswa di sekolah menengah: Kajian teoritis dan implikasinya dalam pembelajaran modern menggunakan model pembelajaran PBL (problem-based learning). Jurnal Review Pendidikan dan Pengajaran, 8(4), 8440–8445. https://doi.org/10.31004/jrpp.v8i4.53575
  17. Permatasari, D. I., & Meiyanti. (2020). The relationship of treatment compliance level and the quality of life of elderly patients with hypertension. International Journal of Pharmaceutical Research, 12(4), 2731–2736. https://doi.org/10.31838/ijpr/2020.12.04.377
  18. Purnamasari, E. O., & Ratih. (2023). Analisis profil fungsi hati dan kejadian efek samping antidiabetik pada pasien DM tipe 2 dengan sirosis hepatik. Jurnal Ilmu Kefarmasian, 4(1), 162–172.
  19. World Health Organization. (2003). Adherence to long-term therapies: Evidence for action. WHO.
  20. Yohana, Y., Meiyanti, M., Margo, E., & Kartadinata, E. (2023). Evaluasi pengukuran glukosa darah puasa dan asam urat pada lanjut usia di Kelurahan Angke, Jakarta Barat. Jurnal Dharma Bhakti Ekuitas, 7(2), 123–130. https://doi.org/10.52250/p3m.v7i2.644.
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